OAR@UM Community: /library/oar/handle/123456789/39054 2026-06-12T04:55:06Z 2026-06-12T04:55:06Z Malaria and the traveller Tonna, Antonella Tonna, Ivan /library/oar/handle/123456789/13637 2019-10-31T08:27:36Z 2005-01-01T00:00:00Z Title: Malaria and the traveller Authors: Tonna, Antonella; Tonna, Ivan Abstract: Malaria has reached epidemic proportions. About 40% of the world’s population live in malarious areas. It is estimated that 400 million people are infected by malaria each year and of these, 1-3 million die, mostly children under five years of age. In the year 2000, malaria was estimated to be the cause for the loss of nearly 45 million Disability Adjusted Life Years (DALYs) and this accounts for 13% of all DALYs associated with infectious diseases. Malaria has gained importance in Western Europe, including Malta, mainly due to the increasing tourism to malaria endemic countries. There have been 21 reported cases of malaria in Malta between the years 2000-2003. 2005-01-01T00:00:00Z Drug-induced peptic ulcer disease Vella, Valerie /library/oar/handle/123456789/13636 2018-01-03T15:07:32Z 2005-01-01T00:00:00Z Title: Drug-induced peptic ulcer disease Authors: Vella, Valerie Abstract: For more than a century, peptic ulcer disease has been a major cause of morbidity and mortality. Peptic ulcer disease is a heterogeneous group of disorders involving the gastrointestinal tract and results from an imbalance between the aggressive forces of gastric acid and pepsin and the defensive mechanisms of the gastric mucosa. 2005-01-01T00:00:00Z Ensuring the appropriate use of medicines Cordina, Maria /library/oar/handle/123456789/13635 2017-05-25T10:37:51Z 2005-01-01T00:00:00Z Title: Ensuring the appropriate use of medicines Authors: Cordina, Maria Abstract: The safe and effective use of medicines requires the ongoing collaboration of the various health care professionals involved in patient care. Pharmacists are crucial in ensuring the appropriate use of medicines both in the community and in hospital. The large number of medicines available and the constant efflux of new information, be it safety or regulatory, makes it practically impossible for any one health care professional to be updated on all aspects. 2005-01-01T00:00:00Z The rise and fall of the COX-2 inhibitors Zammit, Mark L. /library/oar/handle/123456789/13634 2018-03-26T13:39:58Z 2005-01-01T00:00:00Z Title: The rise and fall of the COX-2 inhibitors Authors: Zammit, Mark L. Abstract: Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most widely prescribed groups of medicines in clinical practice, their antiinflammatory, analgesic and anti-pyretic properties making them central to the management of osteoarthritis and rheumatoid arthritis. Gastro-intestinal toxicity represents some of the mostserious adverse drug reactions of this class of drugs. In an attempt to minimize these side-effects, selective cyclo-oxygenase-2 (COX-2) inhibitors were developed. In light of increasing concerns regarding their safety, two COX-2 inhibitors – rofecoxib and valdecoxib were withdrawn from the market in September 2004 and April 2005 respectively. Various restrictions have been also imposed on all the other selective COX-2 Inhibitors. 2005-01-01T00:00:00Z