/library/oar/handle/123456789/52261 2025-12-28T22:59:01Z 2025-12-28T22:59:01Z Miruzzi, Mark /library/oar/handle/123456789/52431 2020-03-15T06:11:12Z 2020-01-01T00:00:00Z

Title: NSTEMI in the context of cardiovascular risk factors and co-morbidities Authors: Miruzzi, Mark Abstract: Mr A.N., a 59-year-old male, was referred to casualty by a health centre physician, following the complaint of two episodes of worsening exertional chest pain. He is a known case of hypertension, non-insulin-dependent diabetes mellitus and smokes 1 pack of cigarettes daily. Following appropriate investigations such as electrocardiogram (ECG), cardiac biomarkers and echocardiography, the patient was diagnosed with non-ST elevation myocardial infarction (NSTEMI). The patient is now stable on treatment; however, his overall cardiovascular risk remains high due to factors such as smoking, uncontrolled type 2 diabetes, hypertension and hypercholesterolaemia. This case highlights the importance of measuring global cardiovascular risk since this has important treatment and follow-up implications; importantly, ischaemic heart disease can be primarily or secondarily prevented through non- pharmacological or pharmacological alteration of the cardiovascular risk factors.

2020-01-01T00:00:00Z Xuereb, Hannah Al Gededi, Adam /library/oar/handle/123456789/52430 2020-03-15T06:11:30Z 2020-01-01T00:00:00Z

Title: An acute case of expressive aphasia following ischaemic stroke Authors: Xuereb, Hannah; Al Gededi, Adam Abstract: Mr. D.C. is a 75-year old gentleman brought to casualty after a neighbour found him unable to speak. Since he was severely aphasic, he was unable to give a proper history. The patient was able to understand commands, making this a pure expressive aphasia. He was also noted to have right hemiparesis and right facial weakness. On examination, Mr D.C. was found to have 0/5 power on the right half of his body and 3/5 power on the left side of his body using the MRC muscle power assessment scale. He was noted to have right facial weakness in an upper motor neurone lesion pattern. He was urgently admitted to a medical ward and a CT scan was requested. The scan confirmed a left middle cerebral artery (MCA) ischaemic infarct affecting the basal ganglia and Broca’s Area in the inferior frontal lobe.

2020-01-01T00:00:00Z Debono, Gabriella /library/oar/handle/123456789/52402 2020-03-15T06:10:28Z 2020-01-01T00:00:00Z

Title: Familial paroxysmal hypokalaemic paralysis (hypoKPP) Authors: Debono, Gabriella Abstract: Case Summary: Demographic Details: Mr. SF, male, South African was referred by his general practitioner A 26-year-old South African gentleman was referred to the Neurology Outpatient department due to occasional episodes of bilateral muscle weakness in the lower limbs. The attacks last for approximately 1 hour and may result in complete muscle paralysis. The severe attacks of bilateral lower limb paralysis are uncommon. The most severe attack he had ever experienced lasted for 19 hours when he was 19 years of age. Mr. SF noticed that stress, carbohydrate-rich meals and exercise triggered recurrent attacks of muscle weakness. The patient’s grandfather, father and sister have been diagnosed with ‘Familial Paroxysmal Hypokalaemic Paralysis’ (hypoKPP). The father had a positive genetic diagnosis from a muscle biopsy. Mr. SF believes that he has inherited the genetic condition, however, he was never tested for the mutation. When the patient suffers an attack of muscle weakness, he takes potassium supplements and rests at home and symptoms resolve.

2020-01-01T00:00:00Z Hallett, Kimberley /library/oar/handle/123456789/52401 2020-03-15T06:10:45Z 2020-01-01T00:00:00Z

Title: Guillain-Barré syndrome Authors: Hallett, Kimberley Abstract: Mr G.B. presented to casualty with bilateral weakness in distal lower limbs which was progressive. He had a history of gastrointestinal illness with severe diarrhoea. On examination he had decreased deep tendon reflexes (ankle jerk) and an unsteady gait. A lumbar puncture was done and the findings were unremarkable. An EMG was also done and confirmed Guillain-Barré Syndrome. He was treated with intravenous immunoglobulin and physiotherapy and he is currently still in hospital recovering well.

2020-01-01T00:00:00Z