/library/oar/handle/123456789/40291 2025-11-10T06:18:53Z /library/oar/handle/123456789/40435 Title: A cameo mention of gamma-glutamyltransferase (GGT) [book review] Abstract: In a conjectural universe where a boy is resurrected as a zombie by a necromancer, and a young girl is cursed to assume the semblance of a middle-aged man, being able to revert to her original self when drunk, it is interesting, somewhat unexpected and refreshing to hear the said character specifically, very briefly, voice concern that her gamma-glutamyltransferase (GGT) levels were abnormally high. 2018-01-01T00:00:00Z /library/oar/handle/123456789/40434 Title: New developments in breast cancer detection Authors: Vassallo, Pierre Abstract: Imaging options for breast cancer detection have changed significantly over time. There are two goals that drive technological change in breast cancer imaging: a. improvement in diagnostic accuracy and b. reduction in radiation exposure to the breast. The gold standard for breast cancer detection has long been the standard two-plane mammogram; this was initially obtained using conventional film/screen technology and later with full field digital mammography (FFDM), which improved image quality and reduced radiation exposure. Digital breast tomosynthesis (DBT) integrates tomography into digital mammographic technology. This imaging method obtains multiple slices through the thickness of the breast thereby reducing interference from tissue overlap, which is particularly advantageous in dense breasts. The current practice is to start with FFDM as the initial screening test and to proceed to DBT only if questionable findings are noted on FFDM. 2018-01-01T00:00:00Z /library/oar/handle/123456789/40433 Title: Migraine Authors: Piscopo, Naomi; Cauchi, Maria Abstract: Migraine is a very common neurological disorder affecting people from numerous age groups and it has been a subject for ongoing research over the past years. Studies have described vascular and neurological pathways as well as cortical spreading depression as being the underlying mechanisms responsible for the symptomatology of the disorder. Multiple triggers have been implicated, out of which genetic susceptibility is very significant. The varied clinical picture of migraine has led to the development of various forms of management ranging from non-specific to very specific preventive, acute and chronic treatment. 2018-01-01T00:00:00Z /library/oar/handle/123456789/40432 Title: Moorfields eye hospital, AI and paradigm shifts Abstract: The application of AI in medicine has always intrigued clinicians, so much so that Elsevier started publishing the journal Artificial Intelligence in Medicine way back in 1989. To put you into perspective, this was a period where we experienced the initial years of marketing of fluoxetine & lovastatin [the first statin], as well as the fall of the Berlin Wall. Way back in 1989 Artificial Intelligence in Medicine discussed ‘Machine over mind’, ‘‘Deep’ models and their relation to diagnosis’, ‘Expert systems in laboratory medicine and pathology’ and the likes. 2018-01-01T00:00:00Z