/library/oar/handle/123456789/49445 2025-11-10T21:41:43Z /library/oar/handle/123456789/49494 Title: Atypical presentation of a rib chondrosarcoma Authors: Zahra, Samuel Abstract: Background: This case report represents a variation from the typical characteristics of an uncommon cardiothoracic pathology, i.e rib chondrosarcomas. Usually this pathology is seen in patients over 40 years of age and grows relatively slowly, taking around 2 years to present clinically. Case Presentation: Our patient was an asymptomatic and healthy 27 year old male who presented with a large right sided thoracic mass. CT scaning revealed an inhomogeneous lesion around 6cm in diameter, arising from the 8th right rib, with no obvious signs of aggressive type of growth and no evidence of metastatic spread. The decision was taken to excise the lesion based on clinical and radiological evidence. Histopathological analysis was carried out at two centres and reported a Grade II 55mm x 48mm x 43mm show with a variably cellular tumour consistent with chondrosarcoma. The case was discussed with the oncological team who advised no need for further treatment given histology and radiological report, except clinical and radiological surveillance. Conclusions: Chondrosarcomas are the 3rd commonest type of bone tumour however it is considered rare for them to originate from the ribcage in a young individual over a relatively short time span. CT scanning is considered the gold standard image and surgery as the main form of management. 2019-10-01T00:00:00Z /library/oar/handle/123456789/49493 Title: Gastrointestinal metastasis of infiltrating lobular carcinoma of the breast : four case reports and literature review Authors: Doyle, Belma; Palmier, Andrew; Magri, Stephanie; Caruana Dingli, Gordon; Ceci, Michelle Abstract: Breast cancer is the most common cancer in women worldwide. The two main types of invasive breast cancer are invasive ductal and invasive lobular carcinoma. The most common sites of breast cancer metastasis encountered are liver, lung, bone and brain. Metastasis of primary lobular breast carcinoma to gastrointestinal (GI) tract is a well-known yet rare occurrence with reported incidence ranging from 2% to 18%. We report four such cases of invasive lobular breast carcinoma metastasizing to the GI tract, and review the literature. 2019-10-01T00:00:00Z /library/oar/handle/123456789/49491 Title: Littoral cell angioma of the spleen : a case report Authors: Grech, Gabriella; Sultana, Angela Abstract: The patient is a 54 year old, presenting with a 4 month history of worsening lower back pain, radiating to both lower limbs. CT Thorax Abdomen and Pelvis was carried out which showed a 6.2cm dense fluid density lesion in the spleen. The case was discussed at the multidisciplinary team meeting and open splenectomy was carried out. Histological diagnosis was consistent with an infarcted littoral cell angioma. 2019-10-01T00:00:00Z /library/oar/handle/123456789/49483 Title: Climate change and human illness : a hot topic? Authors: Torpiano, Paul Abstract: Global climate change, now proven to occur under the influence of human activity, can affect human health and illness. Aside from the risk of natural disasters and diminishing fresh-water supply and arable land, climate change maintains a complex relationship with both communicable and non-communicable forms of illness. The epidemiology of infectious diseases, whether viral, parasitic, or bacterial, has shown to change under the influence of climate, particularly in the case of vector-borne zoonoses. Non-communicable disease, however, including allergic, respiratory, cardiovascular and dermatological, are also influenced by global and regional changes in climate.While further research in this area is recommended, the role of the clinician in educating communities on the negative health impact of climate change, as well as the potential benefit of sustainable healthcare policy, are yet to be defined. 2019-10-01T00:00:00Z