/library/oar/handle/123456789/39261 Mon, 22 Dec 2025 03:02:26 GMT 2025-12-22T03:02:26Z /library/oar/handle/123456789/14294 Title: Molecular classification of colorectal cancer Authors: Briffa, Romina; Grech, Godfrey Abstract: Colorectal cancer (CRC) is a heterogeneous disease with several clinical, pathological, and molecular presentations. A comprehensive and unifying molecular classification would be useful for genotypephenotype correlations, to better understand disease progression, and to predict responses to treatment. Such a classification would be helpful for quickly and efficiently translating results from the laboratory to the clinic and closing the gap between research breakthroughs and actually implementing them clinically. In November 2015, an international consortium consisting of six expert groups published the first consensus on molecular subtypes of colorectal cancer, by bringing together six previously published CRC classifications. Fri, 01 Jan 2016 00:00:00 GMT /library/oar/handle/123456789/14294 2016-01-01T00:00:00Z /library/oar/handle/123456789/14293 Title: Pregnancy and asthma Authors: Gouder, Caroline Abstract: Asthma is the most common chronic condition encountered in pregnancy. Due to lack of evidence on the adverse effects of asthma medication during pregnancy, there is persistent concern regarding use of asthma-related medication throughout the pregnancy, management of exacerbations and asthma management during labour. Several respiratory-related physiological changes are said to occur during pregnancy which could possibly worsen or improve asthma, and asthma as well as its treatment can affect pregnancy outcomes. The aim of this paper is to summarize current literature findings on clinical management issues encountered in this cohort of patients. Fri, 01 Jan 2016 00:00:00 GMT /library/oar/handle/123456789/14293 2016-01-01T00:00:00Z /library/oar/handle/123456789/14292 Title: Insulin therapy in adult type 1 diabetes patients : Multiple Dose Insulin Injection (MDI) or Continuous Subcutaneous Insulin Infusion (CSII) Authors: Abela, Alexia-Giovanna Abstract: Insulin therapy in type 1 diabetes is recommended as multiple dose injections (MDI) or continuous subcutaneous insulin infusion (CSII) to deliver a basal background insulin dose together with bolus insulin doses prior to meals. Use of automated bolus calculators and / or continuous glucose monitors with MDI have been shown to improve glycaemic control in type 1 diabetes patients. Several models of insulin pumps with various features are available. CSII offers greater flexibility with a reduced number of injections but in view of its complexity, patients who will benefit from this therapy need to be carefully selected. Fri, 01 Jan 2016 00:00:00 GMT /library/oar/handle/123456789/14292 2016-01-01T00:00:00Z /library/oar/handle/123456789/14278 Title: Cystitis and its management Authors: Soler, Gillian Abstract: Urinary tract infections are very common. They are responsible for over 6 million patient visits to doctors per year in the United States. These include over 2 million cases that are attributed to cystitis which is the most common urinary tract infection. Cystitis can be defined as an inflammation of the bladder and it may result in pain and discomfort. Women tend to suffer from this condition more than men, although the chance of men acquiring cystitis increases with age. Untreated cystitis can lead to kidney infection, even kidney damage. Treatment for cystitis ranges from over-the counter medications to antibiotics if the cause is an infection. Fri, 01 Jan 2016 00:00:00 GMT /library/oar/handle/123456789/14278 2016-01-01T00:00:00Z