Understanding dopamine鈥檚 role in neurological and psychiatric disorders

Abstract

Dopamine, a key neurotransmitter in the brain, plays a vital role in regulating movement, emotion, and cognition. It is central to the pathology of several major neurological and psychiatric disorders, including Parkinson's disease, schizophrenia, and bipolar disorder. These conditions, though distinct in their symptoms and progression, share a common feature: the disruption of dopamine signalling pathways. Understanding how dopamine dysfunction contributes to these disorders provides insight into their underlying mechanisms and guides the development of effective treatments.