The Department of Applied Biomedical Science, Faculty of Health Sciences, and the Centre for Molecular Medicine and Biobanking, together with the Faculties of ICT and Medicine and Surgery, University of Malta, will be hosting a Summer workshop with special focus on RNA Biology, Transcriptomics, Expression profiling, data handling and how these feed in directly to other protein biology tools.
Course Overview
In this course participants will explore EMBL-EBI resources for transcriptomics and protein biology applications. The sessions focus on browsing, searching and retrieving both functional genomics and protein sequence data, as well as how to classify and predict the function of novel sequences.
Target Audience
This course is aimed at wet-lab and clinical researchers at any career stage within the University of Malta who are working with and/or generating their own transcriptomic and protein sequence datasets. No computational or previous bioinformatics experience is required for this workshop, but an undergraduate level knowledge of biology or biochemistry would be an advantage.
Modules Covered
- ArrayExpress: public database for functional genomics
- Protein sequence databases
- Expression Atlas: Gene expression across species and biological conditions
- Functional protein classification (InterPro)
- Introduction to EMBL-EBI resources and tools.
Learning Outcomes
After this course participants should be able to:
- Identify and use a variety of EMBL-EBI tools to access, retrieve and export data from resources relevant to individual areas of interest.
- Browse, search and retrieve functional genomics data from ArrayExpress
- Find information on the abundance and localisation of RNA (and proteins) in different species and biological conditions.
- Explore gene co-expression and perform gene set overlap analysis.
- Identify information about all aspects of a protein of interest such as function, interactions and disease association, as well as investigate protein homology through similarity searches and alignments.
- Use the InterPro database to classify protein sequences based on underlying protein family models, interpret InterPro annotations, and summarize the application of InterPro data to annotate large-scale sequence datasets.
It will be held between 31 July 2018 and 1 August 2018 at the Faculty of ICR Room TR03, and will be open to all University of Malta faculty and research staff, as well as postgraduate students.
This event is being supported by the Internationalisation Partnership Awards Scheme by MCST – 'Bioinformatics: EBI And UM Teaching (BEAUT)'.
