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/library/oar/handle/123456789/67070| Title: | Small bowel perforation secondary to intestinal tuberculosis in patient with chronic idiopathic myelofibrosis |
| Authors: | Shafi, Mohamed Mohamad, Ikhwan Sani Wan Mokhter, Wan Mokhzani Merican, Siti Rahmah Hashim Zakaria, Zaidi Nik Min, Nik Fatin Amirah Hussain, Faezahtul Arbaeyah |
| Keywords: | Primary Myelofibrosis Tuberculosis, Gastrointestinal Intestine, Small -- Diseases |
| Issue Date: | 2020-12 |
| Publisher: | University of Malta. Medical School |
| Citation: | Shafi, M., Mohamad, I. S., Wan Mokhter, W. M., Merican, S. R. H., Zakaria, Z., Nik Min, N. F. A., & Hussain, F. A. (2020). Small bowel perforation secondary to intestinal tuberculosis in patient with chronic idiopathic myelofibrosis. Malta Medical Journal, 32(3), 107-112. |
| Abstract: | Idiopathic myelofibrosis is a clonal hematopoetic stem cell disorder due to a mutation in the signaling regulator gene Janus Kinase 2 (JAK2).The condition is widely treated with Ruxolitinib which is a JAK2 inhibitor along with prednisolone. However, these treatment despite promising has been linked with the risk of opportunistic infections and reactivation of tuberculosis.We reported a patient with chronic idiopathic myelofibrosis who developed small bowel perforations secondary to flare up of gut tuberculosis. The perforation sites were resected and double barrel stoma was created. |
| URI: | https://www.um.edu.mt/library/oar/handle/123456789/67070 |
| Appears in Collections: | MMJ, Volume 32, Issue 3 MMJ, Volume 32, Issue 3 |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| MMJ32(3)CR4.pdf | 574.89 kB | Adobe PDF | View/Open |
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