Looking for a needle in a haystack!
It takes on a new meaning as we sift through millions of genetic variants in the 1000 whole genome sequences looking for those that alter genes that go out of control during COVID19 resulting in severe COVID19.
We have developed a novel strategy and various bioinformatics tools to search for and hone in on these genetic variants using a combination of approaches. We then gather more evidence from our MAMI Study and COVID19 data.
This is an important step towards finding new drug targets - identifying genes that regulate the factors that go wrong in severe COVID19.
Fingers crossed!