Abstract of the seminar:
Nanocellulose (NC) is a promising biomaterial for biomedical applications due to its excellent structural, chemical, and biological properties. This presentation compares two types of nanocellulose: bacterial nanocellulose (BNC) and SCOBY-derived nanocellulose (SCNC), both of which exhibit similar structural and morphological characteristics.
Functionalisation was carried out using silver nanoparticles (AgNPs) and hyaluronic acid for applications in chronic wound healing and cardiovascular implants, and using hydroxyapatite (HAp) for dental and bone tissue regeneration. The study highlights that while AgNPs significantly improve antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa, high silver concentrations induce cytotoxicity.
Therefore, optimizing silver content is essential to balance antimicrobial effectiveness and biocompatibility. Structural and surface analyses (SEM, FTIR, XRD), as well as mechanical testing, confirm the integrity and suitability of both BNC and SCNC as scaffolding materials. The results support the potential of functionalized nanocellulose in targeted biomedical applications, provided that careful control of functionalization parameters is maintained.